Our approach
People-driven therapeutics
There is a pressing need for new ways to treat disease, but drug development has become increasingly difficult due to high costs and failure rates. Human genetics has the power to transform drug development, because it uses human diversity to identify the basis of disease.
Genetic studies
By studying people who are outliers for medically relevant traits, genetic studies have inspired new therapies to lower cholesterol and treat osteoporosis.
Search
Global Search Network
Genetic studies are only as effective as the people in them. Variant combines anthropology, epidemiology, genetics, and machine learning to identify people who will be most informative. We focus on outliers for traits of medical relevance and populations with rare genetic variants that rise to high frequency.
Sequence
Technology Powered
Using innovative low- and high-pass whole-genome sequencing alongside algorithms we can reduce costs without sacrificing data quality. Our approach is better suited to identify novel and population-specific genetic variants than genotyping arrays, and captures much more of the genome than exome-sequencing.
Discover
From Genomes to Targets
We look for associations between genetic variants and traits that have global medical relevance (i.e. obesity) using statistical genetics. By focusing on outliers and unique populations, we can sequence fewer individuals to make novel discoveries.
Treat
Improving Global Health
We focus on therapeutic areas with global markets and unmet needs including neurodegenerative, autoimmune, and cardiometabolic diseases.